A study aimed to assess the viability of quality of life (QoL) questionnaires for patients with ankylosing spondylitis (AS) or non-radiographic axial spondyloarthritis (nr-axSpA). The results appeared in Health and Quality of Life Outcomes.

Investigators combed through 7 databases in search of randomized controlled trials, cohort trials, and cross-sectional trials. In total, they assessed 22 publications covering 10 instruments. The studies were comprised of 3,085 participants. The primary endpoints of interest were defined as test-retest reliability as well as construct validity. The secondary endpoints included consistency, structural validity, and responsiveness.

The results showed that the most robust QoL assessments were the ankylosing spondylitis QoL and evaluation of ankylosing spondylitis QoL questionnaires. The researchers concluded that these questionnaires are reliable disease-specific methods for assessing AS and nr-axSpA.

Reference: He Q, Luo J, Chen J, et al. The validity and reliability of quality of life questionnaires in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review and meta-analysis. Health Qual Life Outcomes. 2022;20(1):116. doi:10.1186/s12955-022-02026-5

Link: https://pubmed.ncbi.nlm.nih.gov/35907948/