Researchers have identified a potential link between migraine duration and a decrease in central choroidal thickness (CCT), according to a study published in Photodiagnosis and Photodynamic Therapy.

In this study, investigators assessed 38 patients (34 female, 4 male) diagnosed with migraine and 32 healthy controls (19 female, 13 male) using optical coherence tomography angiography (OCTA). They then measured optic disc, central macular vascular perfusions, and CCT.

According to the results, the mean optic disc perfusions were 44.77±1.93% and 45.25±1.43 % in migraine and the control group, respectively (p=0.25). The mean central macular vascular perfusions were 20.50±8.20% and 18.65±7.46% in the migraine and contol groups, respectively (p=0.32). The results showed an appreciable negative correlation between CCT and the duration of migraine history (p=0.004).

“The macular and peripapillary microvasculature were not significantly different in patients with migraine [compared with healthy controls],” the authors concluded. “As the duration of migraine prolonged, a significant decrease in choroidal thickness was observed.”

Source: Photodiagnosis and Photodynamic Therapy


Keywords: Choroidal thickness, Macular perfusion, Migraine, Optic disc perfusion, Optical coherence tomography angiography