The risk of second malignant neoplasms (SMNs) in patients with diffuse large B-cell lymphoma (DLBCL) may vary depending on the primary extranodal site, according to a study. Compared to the general population, patients with extranodal DLBCL were at a much greater risk of SMN. The 10-year risk of SMN varied widely depending on the site of the primary DLBCL diagnosis, the authors noted.

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