A study found an association between serum uric acid (SUA) and patient’s global assessment of disease activity (PtGA) and mental health outcomes in men with axial spondyloarthritis (axSpA). The findings were reported in BMC Musculoskeletal Disorders.

Researchers assessed data from a NASA study on males with axSpA. The outcomes of interest were defined as PtGA, BASDAI, ASDAS-CRP, BASFI, and SF-36. Overall, the study analyzed 102 male patients with axSpA. The investigators used the autoregressive Generalized Estimation Equation (GEE) model to discern the links between outcomes and SUA. The study findings showed serum acid levels were correlated with PtGA, independent of age, gender, and symptom duration confounders.

Reference: Cai M, Liu W, Wu Y, Zheng Q, Liu D, Shi G. The serum uric acid is longitudinally related to patients global assessment of disease activity in male patients with axial spondyloarthritis. BMC Musculoskelet Disord. 2022;23(1):717. doi:10.1186/s12891-022-05657-3

Link: https://pubmed.ncbi.nlm.nih.gov/35897055/