A study identified several important predictors of residual tumors at time of second resection following the initial transurethral resection of bladder tumor (TUR-BT) in patients with pT1 tumors. The findings were reported in Actas Urologicas Españolas.
Researchers assessed 144 patients with pT1 who underwent a second resection within 2 to 6 weeks following initial TUR-BT. The follow-up period was 53 months.
Following analysis, the researchers observed that tumor grade, concomitant carcinoma in situ, tumor appearance, and variant histology were all observed to be significant factors for residual tumor. Analysis showed that tumor grade was the only independent predictor of residual tumor at the time of second resection.
According to the results, highest-risk patients had more than a 90% residual tumor probability at the time of second resection, while patients at lowest risk had an approximately 25% detection probability.
Reference: Culpan M, Kazan O, Cansu Acar H, Iplikci A, Atis G, Yildirim A. The probability of residual tumor detection in the second transurethral resection of pT1 urothelial bladder cancer according to the risk factors. Actas Urol Esp (Engl Ed). 2022;S2173-5786(22)00045-2. doi:10.1016/j.acuroe.2022.05.001