In an observational longitudinal cohort study, researchers aimed to see if established migraine trigger factors and daily adherence to recommendations of a healthy lifestyle are linked to a reduced likelihood of migraine attacks. Participants in the study with episodic migraine tracked their symptoms of headache along with their daily exposure to trigger factors for 90 days through a migraine-headache electronic diary. The study included 1,125 participants with a total of 14,080 migraine attacks. Twenty-four out of 47 triggers were seen to be more commonly connected to a reduced rather than heightened risk of migraine attacks. Caffeine, alcohol, chocolate, happiness, relaxedness, sleep factors, and physical activities were factors this was most noticeable for. The recommendation of avoiding known triggers was challenged in this analysis, as many triggers were seen as protectors in a non-negligible number of participants.

Reference: Casanova A, Vives-Mestres M, Donoghue S, Mian A, Wöber C. The role of avoiding known triggers, embracing protectors, and adhering to healthy lifestyle recommendations in migraine prophylaxis: Insights from a prospective cohort of 1125 people with episodic migraine. Headache. 2023;63(1):51-61. doi:10.1111/head.14451