Researchers of a study looked to identify the distinct influence of the main manifestations of psoriatic arthritis (PsA) in three areas: work disability, physical function, and quality of life (QoL). The Adelphi 2018 PsA Disease-Specific Program was used for data. Dactylitis, enthesitis, axial involvement, psoriasis, and peripheral arthritis were the manifestations of PsA that were used in this analysis. Out of patients in the study with PsA (N=2,222), 77.0% had active psoriasis and 64.4% had peripheral arthritis, with 5.9% having enthesitis, 6.8% with dactylitis, 10.2% with inflammatory back pain, and 3.6% with sacroiliitis, respectively. Researchers of this study highlighted the need for treatments that aimed at the entire spectrum of symptoms of PsA to lessen the disease burden, as majority of the PsA manifestations were found to be independently linked to both worse general and PsA-specific QoL, physical function, and work disability.

Reference: Walsh JA, Ogdie A, Michaud K, et al. Impact of key manifestations of psoriatic arthritis on patient quality of life, functional status, and work productivity: findings from a real-world study in the United States and Europe [published online ahead of print, 2023 Jan 24]. Joint Bone Spine. 2023;105534. doi:10.1016/j.jbspin.2023.105534