To develop enhanced pharmacological and non-pharmacological approaches for pain relief during labor, it is crucial to identify a neural signature that is associated with labor pain. In this article, the authors describe using functional magnetic resonance imaging to compare brain activation maps and functional neural networks in laboring women who received epidural anesthesia and those who did not. Study results confirm the existence of a neural pattern associated with labor pain and demonstrate that epidural anesthesia can modify this pattern.

Reference: Wang JJ, Yang FG, Tsai CC, Chao AS. The neural basis of pain during labor. Am J Obstet Gynecol. 2023 Mar 20:S0002-9378(23)00113-8. doi: 10.1016/j.ajog.2023.02.012. Epub ahead of print. PMID: 36948996

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