A recent study characterized musculoskeletal (MSK) surgeries among psoriatic arthritis (PsA) patients and determined factors associated with first MSK surgery, which were related to PsA. A cohort of 1574 patients with PsA from a single center, who underwent MSK surgery between 1978 and 2019, were identified using the Classification Criteria for Psoriatic Arthritis. Charts were reviewed to confirm that the surgeries were related to MSK and caused by PsA, and descriptive statistics were used to determine the prevalence and types of MSK surgeries.
A heightened risk of surgery was linked to the total amount of damaged joints, tender or swollen joints, nail lesion presence, greater Health Assessment Questionnaire scores, positive HLA-B27, and higher rates of erythrocyte sedimentation. Through a multivariate model, greater Psoriasis Area Severity Index had a protective impact. No statistical significance was seen with biologics. It was concluded that markers of cumulative disease activity and damage were linked to a higher risk of needing surgery.
Reference: Kwok TSH, Sutton M, Cook RJ, Pereira D, Chandran V, Gladman DD. Musculoskeletal Surgery in Psoriatic Arthritis: Prevalence and Risk Factors. J Rheumatol. 2023;50(4):497-503. doi:10.3899/jrheum.220908
