The monitoring of ictal semiology signs in temporal lobe epilepsy (TLE) and temporal plus epilepsy (TPE) is mission critical, according to the results of a study published in the journal Neurosciences.
Researchers of this study sought to discern if there exists a link between ictal semiology signs, their localization/lateralization value after intracranial electroencephalography (EEG) monitoring, and surgical outcomes.
In this retrospective study that took place between January 2008 and December 2018, the research team retrieved data on 464 patients, of which 181 had intracranial electrode monitoring. Final analysis comprised 48 patients (mean age, 27), of which 15 had TPE.
Following analysis, the results showed that early-onset ictal manual automatism, oral automatism, late-onset dystonic posture, and late head-turning were markedly linked to TLE without significant lateralization value. The ictal onset zone’s localization was significant between the scalp and intracranial EEG findings in mesial TLE patients, the researchers noted.
They concluded: “Our results are consistent with previous studies and confirm the importance of ictal semiology signs in TLE and TPE. The addition of intracranial EEG monitoring in these cases helped improve the surgical outcomes.”
Keywords: temporal lobe epilepsy, temporal plus epilepsy, ictal semiology