In a study of patients with plaque psoriasis, researchers were able to utilize high-frequency ultrasound to evaluate the impact of treatment on plaque vascularization.

Ten patients with plaque psoriasis were enrolled in the analysis. The researchers used a 70 MHz probe to assess the superficial hyperechoic band, the subepidermal hypoechoic band (SLEB), and the vascularization of the plaque before and up to one month after treatment.

According to the ultrasound, average superficial hyperechoic band thickness was 0.2157 mm pre-treatment, 0.1611 mm after 15 days, and 0.1354 mm after 30 days (P<0.05). SLEB thickness was 0.7535 mm, 0.3300 mm (P<0.05), and 0.2007 mm (P<0.05), respectively. Average vascularization percentages at baseline, 15 days, and 30 days were 50.21%, 13.15% (P<0.05), and 5.97%, respectively.

Reductions in SLEB thickness after 15 days and hyperechoic superficial band thickness after 30 days were both statistically significant.

Source: Skin Research and Technology