Researchers of a randomized study in Hong Kong (n=68; mild–moderate Parkinson’s disease [PD]) compared 8 weekly 90-minute sessions of a modified mindfulness meditation program with stretching and resistance training exercise. Assessments occurred at baseline during civil unrest (T0), immediately post-intervention (T1), and 3 months later amid early COVID-19 (T2). Mindfulness participants showed significantly reduced depressive symptoms at week 8 (d = −1.66; 95% CI, −3.31 to −0.02) and maintained emotional stability at week 20 (d = 2.08; 95% CI, 0.59 to 3.56). Both groups demonstrated small–moderate cognitive gains (d = 0.36–0.37; P=.006–.011). Psychospiritual outcomes improved more with mindfulness (including greater mindfulness at T1 and non-judging awareness at T2), while the exercise group improved motor symptoms and some cognition at T1 but showed worsening emotional reactivity at T2.
The authors conclude that integrating mindfulness into motor-oriented PD rehabilitation may bolster resilience and reduce psycho-cognitive morbidities—benefits that appeared especially relevant under real-world stressors like social unrest and a pandemic. They recommend incorporating mindfulness tips into public “anti-pandemic” guidance and encourage clinicians to add mindfulness to evidence-based exercise protocols. Limitations include convenience sampling, a modest sample size, and phone-only follow-up at T2 (limiting detailed motor and mobility assessment).
Reference: Petrullo J. Mindfulness Training May Improve Outcomes for People With Parkinson Disease. AJMC. Published January 30, 2023. Accessed October 23, 2025. https://www.ajmc.com/view/mindfulness-training-may-improve-outcomes-for-people-with-parkinson-disease
