A study suggests that bariatric surgery is effective for type 2 diabetes mellitus (T2DM) remission. The results were published in Obesity Surgery.

In this study, researchers combed PubMed, Scopus and Web of Science to perform a network meta-analysis. The aim of the analysis was to discern the comparative effectiveness of the different procedures and medical treatment in terms of full T2DM remission, weight loss, complications and cardiometabolic biomarkers. They used Cochrane Risk of Bias Tool and Confidence in Network Meta-Analysis (CINeMA) to assess data efficacy. In total, 11 primary studies were analyzed.

According to the results, laparoscopic one-anastomosis gastric bypass (LOAGB) was found to be one of the most effective treatments to yield full remission of T2DM. With respect to high-density lipoprotein and weight change, all surgical treatments were shown to be more effective than medical treatment. While confidence rating in this study was overall moderate, the researchers noted, most studies had high risk of performance and detection bias.

“Bariatric surgery seems to be effective for T2DM remission. LOAGB appears to be a good option in this context, and a possible alternative to laparoscopic duodenal switch, but the included primary studies in our review are not sufficiently powered to establish a more definitive conclusion,” the researchers noted. “More studies with longer follow-up times are needed to comprehensively assess bariatric surgery in T2DM.”

Keywords: Biliopancreatic diversion, Diabetes; Laparoscopic Roux-en-Y gastric bypass, Laparoscopic adjustable gastric banding, Laparoscopic duodenal switch, Laparoscopic one-anastomosis gastric bypass, Laparoscopic sleeve gastrectomy, Metabolic surgery, Vertical banded gastroplasty

Link: https://pubmed.ncbi.nlm.nih.gov/34611827/