Speech Patterns and Enunciation for Encephalopathy Determination

Early diagnosis, treatment, and management helps hepatic encephalopathy, so researchers conducted a single‐center prospective cohort study that included participants with cirrhosis with overt HE (OHE), cirrhosis without hepatic encephalopathy, and patients without liver disease, for the purposes of analyzing speech patterns, and if those patterns could assist with diagnosis and monitoring. When speech rate and precision ratings were combined into a single speech severity metric, the impairment of participants with OHE was more severe than all other groups. Monitoring of speech does present utility for the diagnosis and monitoring of hepatic encephalopathy.

Reference: Moon AM, Kim HP, Cook S, Blanchard RT, et al. patterns and enunciation for encephalopathy determination-A prospective study of hepatic encephalopathy. Hepatol Commun. 2022 Oct;6(10):2876-2885. doi: 10.1002/hep4.2054. Epub 2022 Jul 21. PMID: 35861546; PMCID: PMC9512449.

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