The skin’s health and resilience are significantly influenced by trace elements. Deficiencies or imbalances in these micronutrients are linked to a range of dermatological conditions including acne, eczema, psoriasis, vitiligo, and alopecia areata. Both internal (diet, supplementation) and external (topical formulations) approaches are used to replenish these nutrients. However, the increasing use of cosmetics introduces potential exposure to toxic metals such as lead and mercury, raising safety concerns and highlighting the need for regulatory oversight. This review emphasizes the dual role of trace elements as both therapeutic agents and potential hazards in dermatological care.
Emerging evidence underscores the therapeutic value of trace element supplementation, particularly in conditions marked by deficiency, such as reduced zinc and selenium levels in psoriasis. Mineral balance is essential for skin regeneration, barrier maintenance, and protection against oxidative stress. Nutraceuticals, phytotherapeutics, and mineral-enriched cosmeceuticals are gaining popularity for their skin-enhancing properties. Traditional treatments like balneotherapy continue to demonstrate benefits through mineral-rich environments. Nonetheless, the presence of toxic elements in personal care products remains a critical issue. As such, maintaining mineral homeostasis while avoiding harmful exposures is vital to promoting skin health and managing chronic dermatoses.
Reference: Bjørklund G, Shanaida M, Hangan T, et al. The role of trace elements for the function and health of the skin. J Trace Elem Med Biol. 2025 Jun;89:127674. doi: 10.1016/j.jtemb.2025.127674. Epub 2025 May 24. PMID: 40460725.
