In a recent analysis, researchers utilized data from the National Health and Nutrition Examination Survey (NHANES) to examine the relationships between environmental PFAS, phenol, and paraben exposure with previous cancer diagnoses, focusing on potential gender differences. Prostate cancer and breast cancer were the most commonly reported malignancies among men and women respectively. No associations were found between PFAS biomarkers and previous cancer diagnoses in men. Several PFAS biomarkers showed positive associations with the odds of previous melanoma among women. Notably, increased odds of previous reproductive cancer diagnosis among women was linked to certain phenol compounds.
Reference: Cathey AL, Nguyen VK, Colacino JA, Woodruff TJ, Reynolds P, Aung MT. Exploratory profiles of phenols, parabens, and per- and poly-fluoroalkyl substances among NHANES study participants in association with previous cancer diagnoses. J Expo Sci Environ Epidemiol. 2023;33(5):687-698. doi:10.1038/s41370-023-00601-6