There exists a potential link between migraine and dementia, according to a study published in Acta Neurologica Scandinavica.

To conduct this study, researchers queried PubMed, EBSCO, Web of Science, and EMBASE from inception to April 1, 2021, using subject and free words. Software was used to calculate the risk ratio (RR) of dementia in patients with migraine, while a subgroup and sensitivity analyses were conducted to assess the source of heterogeneity. In total, the researchers assessed five published cohort studies covering a total of 249,303 individuals.

According to the results, migraine was associated with increased risk of all-cause dementia (RR = 1.34, 95% confidence interval [CI]: 1.13-1.59) and Alzheimer’s disease (AD) (RR = 2.49, 95% CI: 1.16-5.32). However, the study did not discern any association between migraine and risk of vascular dementia (RR = 1.51, 95% CI: 0.77-2.96).

“Our results revealed that migraine was a potential risk indicator for AD and all-cause dementia,” the researchers concluded.



Keywords: AD, dementia, meta-analysis, migraine, risk