Researchers aimed to assess the frequency of fatigue as well as its severity in those with psoriatic arthritis (PsA) in addition to the impact of fatigue on patient-reported outcomes. Patients included in the study had PsA that had been confirmed by a physician, and fatigue was gathered as a binary variable as well as through the severity of it. A total of 831 patients were included in the study, with a mean age of 47.5 years and mean disease duration of 5.3 years. Fatigue had been reported in 78.3% of patients. Those who experienced more severity in fatigue also had longer disease duration, greater PSA severity, levels of pain, swollen and tender joint counts, and body surface area impacted by psoriasis. Fatigue was underreported and under recognized by physicians. Greater severity of fatigue was found to be linked to worsened physical functioning, work productivity, and health-related quality of life.

Reference: Gossec L, Walsh JA, Michaud K, et al. Effect of Fatigue on Health-Related Quality of Life and Work Productivity in Psoriatic Arthritis: Findings From a Real-World Survey. J Rheumatol. 2022;49(11):1221-1228. doi:10.3899/jrheum.211288