Researchers of a study analyzed the elevated risk of autoimmune-related diseases in children and adolescents diagnosed with inflammatory bowel disease (IBD). The research indicated that young patients with early-onset IBD are particularly susceptible to developing conditions such as psoriatic arthritis, spondyloarthritis, celiac disease, rheumatoid arthritis, and both types of diabetes. Notably, psoriatic arthritis and spondyloarthritis were found to occur earlier in the IBD group compared with a matched non-IBD reference group, suggesting a strong link between early-onset IBD and these specific autoimmune disorders.
The study spanned from 1980 to 2021 and involved 6,822 patients with IBD and 337,728 matched references. The results revealed significantly higher risks for several autoimmune diseases in the IBD group, with the highest adjusted hazard ratios seen for psoriatic arthritis (4.72) and spondyloarthritis (5.21). These findings underscore the necessity of monitoring young IBD patients for early signs of these conditions, emphasizing the importance of vigilant clinical follow-up.
Reference: Brooks A. Early-Onset IBD Linked to Greater Risk of Diseases with Possible Autoimmune Pathogenesis. HCPLive. Published March 26, 2024. Accessed April 19, 2024. https://www.hcplive.com/view/early-onset-ibd-linked-greater-risk-diseases-autoimmune-pathogenesis
Link: https://www.hcplive.com/view/early-onset-ibd-linked-greater-risk-diseases-autoimmune-pathogenesis
