Researchers of a study conducted a systematic review and meta-analysis to evaluate inter- and intraobserver variability of inflammatory bowel disease (IBD) endoscopic scoring systems. Thirteen observational studies were analyzed, focusing on scoring systems like the endoscopic Mayo Score, Ulcerative Colitis Endoscopic Index of Severity, Crohn’s Disease Endoscopic Index of Severity, and Simple Endoscopic Score for Crohn’s Disease. Interobserver agreement ranged from moderate to good (0.58-0.80), while intraobserver agreement varied from good to very good (0.75-0.91).
The study emphasizes the need to address endoscopic scoring variability for more accurate patient assessment, enhancing clinical management and trial data precision. Given significant heterogeneity across studies, improving interobserver agreement is crucial for reliable outcomes, aiding patient stratification and treatment evaluation. Standardized protocols or training are essential to minimize variability, ultimately optimizing clinical decision-making and improving therapeutic interventions for inflammatory bowel disease.
Reference: Hashash JG, Yu Ci Ng F, Farraye FA, et al. Inter- and Intraobserver Variability on Endoscopic Scoring Systems in Crohn’s Disease and Ulcerative Colitis: A Systematic Review and Meta-Analysis. Inflamm Bowel Dis. 2024:izae051. doi: 10.1093/ibd/izae051.
