Researchers evaluated changes in gut microbiota during narrow-band ultraviolet B (NB-UVB) therapy. Stool samples from 22 participants, including 13 psoriasis patients and nine healthy controls, were analyzed using 16S rRNA sequencing before and after NBUVB therapy. Following NB-UVB treatment, certain bacteria were more enriched in responders but not non-responders. Additionally, serum vitamin D levels significantly increased after NB-UVB treatment.The study suggests that NB-UVB therapy can alter gut microbiota, and these changes may be treatment-specific and influence treatment response.
Reference: Rungjang A, Meephansan J, Payungporn S, et al. Alteration of gut microbiota during narrowband ultraviolet B therapy in psoriasis: A preliminary study. Exp Dermatol. 2022 Aug;31(8):1281-1288. doi: 10.1111/exd.14631. Epub 2022 Jun 29. PMID: 35737868.
